IPB

Здравствуйте, гость ( Вход | Регистрация )

Предстоящее мероприятие:

 
Reply to this topicStart new topic
> laramsapparelsshop
Zhuyeqing
сообщение Jun 3 2019, 11:11
Сообщение #1





Группа: Пользователи
Сообщений: 275
Регистрация: 9.5.2018
Из: '
Пользователь №: 6 321



Репутация:   0  


by Christian Edwards


SYDNEY Jamon Brown Rams Jersey , April 24 (Xinhua) -- In a remarkable breakthrough for global gene science, researchers at the Australian University of New South Wales (UNSW) have for the first time delivered regenerative gene therapy, successfully re-growing auditory nerves - effectively recreating tonal sounds for the deaf.


By employing electrical pulses delivered from a cochlear implant through auditory senses, the breakthrough brings hope to millions of people around the world that previously could not detect the tones that deliver music or other more complex sounds.


The research, published Thursday in the prestigious journal Science Translational Medicine also heralds a possible new way of treating a range of neurological disorders, including Parkinson's disease Rob Havenstein Rams Jersey , and psychiatric conditions such as depression through this novel way of delivering gene therapy.


"People with cochlear implants do well with understanding speech, but their perception of pitch can be poor, so they often miss out on the joy of music," says UNSW Professor Gary Housley, senior author of the research paper.


"Ultimately, we hope that after further research Tyler Higbee Rams Jersey , people who depend on cochlear implant devices will be able to enjoy a broader dynamic and tonal range of sound, which is particularly important for our sense of the auditory world around us and for music appreciation," said Professor Housley, who is also the Director of the Translational Neuroscience Facility at UNSW Medicine.


The research, supported by Cochlear Limited through an Australian Research Council Linkage Project grant, has been five years in development.


The work centers on regenerating surviving nerves after age- related or environmental hearing loss Jared Goff Rams Jersey , using existing cochlear technology. The cochlear implants are "surprisingly efficient" at localized gene therapy in the animal model, when a few electric pulses are administered during the implant procedure.


"This research breakthrough is important because while we have had very good outcomes with our cochlear implants so far, if we can get the nerves to grow close to the electrodes and improve the connections between them, then we'll be able to have even better outcomes in the future," says Jim Patrick, Chief Scientist and Senior Vice-President Samson Ebukam Rams Jersey , Cochlear Limited.


It has long been established that the auditory nerve endings regenerate if neurotrophins a naturally occurring family of proteins crucial for the development, function and survival of neurons are delivered to the auditory portion of the inner ear, the cochlea.


But until now, research has stalled because safe, localized delivery of the neurotrophins can't be achieved using drug delivery, nor by viral-based gene therapy.


Professor Housley and his team at UNSW developed a way of using electrical pulses delivered from the cochlear implant to deliver the DNA to the cells close to the array of implanted electrodes. These cells then produce neurotrophins.


"No-one had tried to use the cochlear implant itself for gene therapy Josh Reynolds Rams Jersey ," says Professor Housley. "With our technique, the cochlear implant can be very effective for this."


While the neurotrophin production dropped away after a couple of months, Professor Housley says ultimately the changes in the hearing nerve may be maintained by the ongoing neural activity generated by the cochlear implant.


"We think it's possible that in the future this gene delivery would only add a few minutes to the implant procedure," says the paper's first author, Jeremy Pinyon, whose PhD is based on this work. "The surgeon who installs the device would inject the DNA solution into the cochlea and then fire electrical impulses to trigger the DNA transfer once the implant is inserted."


Integration of this technology into other "bionic" devices such as electrode arrays used in deep brain stimulation (for the treatment of Parkinson's disease and depression John Johnson Rams Jersey , for example) could also afford opportunities for safe, directed gene therapy of complex neurological disorders.


"Our work has implications far beyond hearing disorders," says co-author Associate Professor Matthias Klugmann, from the UNSW Translational Neuroscience Facility research team. "Gene therapy has been suggested as a treatment concept even for devastating neurological conditions and our technology provides a novel platform for safe and efficient gene transfer into tissues as delicate as the brain."

Optimum natural fertility depends upon excellent general health, which can only be attained when our body's metabolic processes are nourished and well balanced. This is where the liver comes in.

The liver is one of the most important organs in the body because it governs approximately 500 metabolic processes to ensure optimum health and fertility. These are categorized into nine main ones and include: Carbohydrate metabolism--assisting to maintain blood sugar levels; fat metabolism and cholesterol balance; protein metabolism including disposing of and re-making blood as well as other body building blocks; storage of blood; bile salts production to assist digestion; storage of vitamins (A, D Cooper Kupp Rams Jersey , E, K, B, C) and minerals (iron, potassium, copper Gerald Everett Rams Jersey , zinc); production of heat, breakdown and elimination of hormones essential for hormonal balance and detoxification.

The liver is the largest human internal organ and one of the few capable of natural regeneration--as little as 25% of remaining liver can regenerate into a whole liver again. Ensuring the liver has what is required for optimum function is essential for peak general health and fertility.

The way of ensuring optimum liver function is the same (of course) as the approach used to help couples overcome infertility to have a healthy baby, it includes a low toxin lifestyle: a healthy, clean diet; no coffee or alcohol consumption; avoidance of chemicals, recreational substances, smoking and any o. Wholesale Jerseys China Cheap Jerseys From China Cheap Jerseys From China Wholesale Jerseys China Cheap Jerseys From China Cheap Jerseys Free Shipping Cheap Authentic NFL Jerseys Wholesale NFL Jerseys China Wholesale NFL Jerseys Cheap Authentic NFL Jerseys

Go to the top of the page
 
+Quote Post

Fast ReplyReply to this topicStart new topic
1 чел. читают эту тему (гостей: 1, скрытых пользователей: 0)
Пользователей: 0

 



Текстовая версия Сейчас: 23rd July 2019 - 06:16